Professor Jemma C. Hopewell
BSc (Hons) MSc PhD (Cantab) FESC
Professor of Precision Medicine & Epidemiology
- BHF Intermediate Basic Science Research Fellow
- MSc in Global Health Science Module Lead: Genetic Epidemiology
- Visiting Professor, McGill University
Professor Jemma Hopewell leads a team of genetic epidemiologists, clinical fellows, medical statisticians and bioinformaticians in a programme of research focusing on the use of genetic and clinical trial-based studies to investigate the causes and treatments for cardiovascular disease and arrhythmias. She has particular interests in determining predictors of patient response to therapy, using genetics to improve our understanding of drug targets and disease mechanisms, and genomic characterisation of vascular disease and its risk factors, particularly Lp(a).
Jemma leads and collaborates on numerous projects involving CTSU's vascular mega-trials (e.g. HPS, SEARCH, THRIVE, REVEAL), large-scale studies and biobanks (e.g. PROCARDIS, UK Biobank), and international consortia (e.g. METASTROKE, CARDIoGRAMplusC4D, GoLEAD, CATCH-ME). She is a member of the Lp(a) Foundation Scientific Advisory Board, of various clinical trial and genetic study Steering and Analysis Committees, and is currently the Chair of METASTROKE (a collaboration of the International Stroke Genetics Consortium), as well as co-ordinating the MSc in Global Health Science Genetic Epidemiology module.
Hopewell Group - Current Members
- Research Staff
Dr Maysson Ibrahim, Senior Bioinformatician
Federico Murgia, Bioinformatician
Dr Alex Stiby, Senior Genetic Epidemiologist & Statistical Programmer
Dr Elsa Valdes-Marquez, Senior Medical Statistician
Mr Adam Von Ende, Medical Statistician
- DPhil Students
Dr Christian Camm, British Heart Foundation Clinical Research Training Fellow
Dr Parag Gajendragadkar, British Heart Foundation Clinical Research Training Fellow
Sam Smith, Personal Assistant
Assessment of the causal relevance of ECG parameters for risk of atrial fibrillation: A mendelian randomisation study.
Gajendragadkar PR. et al, (2021), PLoS medicine, 18
The Use of Primary Care Big Data in Understanding the Pharmacoepidemiology of COVID-19: A Consensus Statement From the COVID-19 Primary Care Database Consortium
Dambha-Miller H. et al, (2021), Annals of family medicine, 19, 135 - 140
Lp(a) (Lipoprotein[a]), an Exemplar for Precision Medicine: Insights From UK Biobank.
Hopewell JC. et al, (2021), Arteriosclerosis, thrombosis, and vascular biology, 41, 475 - 477
Differential impact of adiposity on risk of atrial fibrillation in men and women in UK Biobank
Camm CJF. et al, (2020), EUROPEAN HEART JOURNAL, 41, 502 - 502
Differential impact of life-long lower LDL-C levels on ischaemic stroke subtypes and coronary heart disease risk among 1 million individuals
Hopewell JC. et al, (2020), EUROPEAN HEART JOURNAL, 41, 2410 - 2410