Christophe Fraser

Christophe Fraser

Senior Group Leader in Pathogen Dynamics, Big Data Institute; Nuffield Department of Medicine

Christophe Fraser is Senior Group Leader in Pathogen Dynamics at the Big Data Institute, and Professor in the Nuffield Department of Medicine. Christophe is interested in studying the population dynamics and epidemiology of pathogens, and translating this knowledge to public health. The primary tools used by his group are mathematical modelling and pathogen genomics.

He trained in theoretical particle physics, and converted to mathematical biology after his PhD, in 1998. He was Royal Society URF and then Professor in the Department of Infectious Disease Epidemiology at Imperial College. He joined the BDI at Oxford in 2016.

Current topics of interest are: HIV virulence; HIV treatment as prevention; HIV genomics; pneumococcal genomics; antibiotic resistance; outbreak response.

Current projects: BEEHIVE is cross-European study of HIV genomics and virulence amongst seroconverters. HPTN071 (PopART) is a cluster-randomized trial of HIV prevention including universal test and treat, in a population of 1.2 million people at high risk in Zambia and South Africa.  PANGEA is a consortium mapping HIV-1 genomic diversity and linking to prevention modelling across sub-Saharan Africa. For MIDAS, we study the spread and dynamics of antibiotic resistance in Streptococcus pneumoniae in the USA. We have been involved in responses to outbreaks, such as SARS in 2003, H1N1pdm in 2009, and more recently MERS and Ebola.

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Recent Publications

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