Genetic drivers of heterogeneity in type 2 diabetes pathophysiology
Journal article
CHEN Z. et al, (2024), Nature
Association between maternal haemoglobin concentrations and maternal and neonatal outcomes: the prospective, observational, multinational, INTERBIO-21st fetal study.
Journal article
Ohuma EO. et al, (2023), The Lancet. Haematology, 10, e756 - e766
Genic constraint against nonsynonymous variation across the mouse genome.
Journal article
Powell G. et al, (2023), BMC genomics, 24
Exome-wide evidence of compound heterozygous effects across common phenotypes in the UK Biobank
Preprint
Lassen FH. et al, (2023)
Discovering cellular programs of intrinsic and extrinsic drivers of metabolic traits using LipocyteProfiler.
Journal article
Laber S. et al, (2023), Cell genomics, 3
Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake.
Journal article
Williamson A. et al, (2023), Nature genetics, 55, 973 - 983
A non-coding variant linked to metabolic obesity with normal weight affects actin remodelling in subcutaneous adipocytes.
Journal article
Glunk V. et al, (2023), Nature metabolism, 5, 861 - 879
The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions
Journal article
ZONDERVAN K. and RAHMIOGLU N., (2023), Nature Genetics
Loci for insulin processing and secretion provide insight into type 2 diabetes risk.
Journal article
Broadaway KA. et al, (2023), Am J Hum Genet
Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts
Journal article
Wang Y. et al, (2023), Cell Genomics, 3
The genetic architecture of changes in adiposity during adulthood
Preprint
Venkatesh S. et al, (2023)
Meta-analysis fine-mapping is often miscalibrated at single-variant resolution
Journal article
Kanai M. et al, (2022), Cell Genomics, 2
Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease
Journal article
Zhou W. et al, (2022), Cell Genomics, 2
A saturated map of common genetic variants associated with human height.
Journal article
Yengo L. et al, (2022), Nature, 610, 704 - 712
Correction: Obesity and risk of female reproductive conditions: A Mendelian randomisation study.
Journal article
Venkatesh SS. et al, (2022), PLoS medicine, 19
Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes.
Journal article
Pervjakova N. et al, (2022), Human molecular genetics, 31, 3377 - 3391
Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies.
Journal article
Gorski M. et al, (2022), Kidney international
Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals.
Journal article
Winkler TW. et al, (2022), Communications biology, 5
Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations.
Journal article
Temprano-Sagrera G. et al, (2022), Journal of thrombosis and haemostasis : JTH, 20, 1331 - 1349
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.
Journal article
Mahajan A. et al, (2022), Nature genetics, 54, 560 - 572