HDRUK Regional Network

Professor Charalambos Antoniades

Radcliffe Department of Medicine

• Cardiovascular research
• Cardiometabolic risk prevention
• Artificial intelligence
• Precision medicine
• Non-invasive imaging

• Oxford Heart Vessels & Fat (ox-HVF) cohort (2011-ongoing)
• The Oxford Risk Factors and Non-invasive imaging (ORFAN) study (2015-ongoing)
• Photon-counting CT for deep cardiovascular phenotyping
• Developing novel radio-multiomic biomarkers for precision diagnostics

Associate Professor Derrick Bennett

Oxford Population Health

• Randomised Trials
• Large-scale observational studies
• Electronic health records
• Metabolomics and proteomics

• CoMPuTE: Complex Multiple long-term conditions Phenotypes, Trends, and Endpoints - end date 2028
• Assessing the utility of untargeted metabolomics for discovery research in the China Kadoorie Biobank  - end date 2025
• Using data from wearable devices to identify novel targets for cardiometabolic disease (obesity, T2DM, NAFLD, & heart failure) - end date 2025
• Can wearables improve the prediction of all-cause mortality, cardiovascular disease, and cancer  in UK Biobank? - end date 2025

Dr Fiona Bragg

Oxford Population Health

• Epidemiology
• Diabetes
• Public Health

• Genetic liability to type 2 diabetes and cause-specific mortality in Mexico City
• Metabolomic profile of genetic liability to type 2 diabetes among Mexican adults
• Relevance of age at diagnosis of type 2 diabetes for cause-specific mortality among Chinese adults
• Type 2 diabetes associated mortality risks among adults in India
• Assessment of the gut microbiome in rural India: a pilot study in the Indian Study of Healthy Ageing

Dr Jennifer Carter

Oxford Population Health

• Global Health
• Nutrition
• Obesity
• Cardiovascular disease

• Association of ultra-processed food consumption and body composition and blood pressure in Brazil and United Kingdom - end date December 2025
• Obesity and non-communicable disease in Malaysia: an imaging study of 6000 adults in the Malaysian Cohort Study - end date September 2026
• Ethnic differences in body composition, bone mineral density and osteoporosis - end date October 2027
• Body composition, cause-specific mortality and outcome ascertainment in low-and-middle-income countries - end date October 2027

Professor Zhengming Chen

Oxford Population Health

• Clinical Trials
• Epidemiology
• Big Data
• Omics

• China Kadoorie Biobank (CKB)

Professor Jim Davies

Big Data Institute

• Model-driven software engineering
• Semantic interoperability
• Data architecture 

• NIHR Oxford BRC Translational Data Science Theme (2022-2027)
• i4i Dementia: digital approaches for early detection and stratification (2023-2028)
• Thames Valley and Surrey NHS Secure Data Environment
• Oxford EPSRC Centre for Doctoral Training in Health Data Science (2022-2027)

Professor Aiden Doherty

Big Data Institute

• Wearable sensors
• Machine learning
• Genomics

• Derived physical activity and sleep variables in UKBiobank
• Open human activity recognition resources
• Computational approaches for cardiovascular disease

Professor John Gallacher

Department of Psychiatry

• Cognitive Health
• Big Data
• Mental wellbeing

• Dementias Platform UK (DPUK)
• BrainWaves
• MND Translational Accelerator
• MND Research Data Catalyst

Professor Richard Haynes

Oxford Population Health

• Clinical Trials
• Kidney Disease
• Cardiovascular disease
• Infectious disease

• EASi-KIDNEY trial - end date 2028
• 3C Study - no end date planned
• RECOVERY trial - no end date planned

Associate Professor Sara Khalid

Nuffield Department of Rheumatology and Musculoskeletal Sciences

• Health Informatics
• Intelligent Patient Monitoring
• Planetary Health
• Real-world Data Science

• Planetary Health Informatics (PHI Lab)
• European Health Data & Evidence Network (EHDEN)
• Observational Health Data Sciences and Informatics (OHDSI)
• Mitigating climate-health inequities with AI and real-world analytics
• BMGF Global Grand Challenges in Catalysing Equitable AI 

Dr Ivan Koychev

Department of Psychiatry

• Clinical Trials
• Dementia Research
• Neuropsychiatry

• Impact of Semaglutide in Amyloid Positivity clinical trial
• FAST Study
• READ OUT Blood Biomarkers Challenge study
• Dementia Trial Accelerator

Associate Professor Bartek Papiez

Big Data Institute

• Medical Image Analysis
• Machine Learning

• Integration of medical imaging and genetic data using machine learning' (2022-2025)
• Artificial Intelligence and Resistance Imaging in Lung Cancer' (2023-2026)
• Artificial Intelligence and medical image analysis for monitoring inflammatory arthritis' (2022-2026)

Professor David Preiss

Oxford Population Health

• Clinical Trials
• Cardiovascular Research
• Diabetes Research

• ASCEND-PLUS (ongoing)
• LENS (2024)
• ORION-4 (ongoing)
• EMPA-KIDNEY (2022)

Professor Daniel Prieto-Alhambra

Nuffield Department of Rheumatology and Musculoskeletal Sciences

Area of expertise

• Real World Evidence
• Pharmaco-epidemiology
• Device Epidemiology

Projects in the Health Data space

• OMOP Common Data Model
• European Medicines Agency's Data Analysis and Real World Interrogation Network (DARWIN EU)
• European Health Data & Evidence Network (EHDEN)
• Observational Health Data Sciences and Informatics (OHDSI)
• HDRUK Real-World Evidence (RWE) Network

Dr Jason Torres

Oxford Population Health

• Genomics
• GWAS
• Genetic admixture
• Polygenic scores

• Imputing multi-omic traits in the Mexico City Prospective Study

Kerrie Woods

Thames Valley and Surrey Secure Data Network

• Real World Data
• Research Data Governance

• Thames Valley Secure Data Environment (SDE)
• NHS Thames Valley and Surrey Secure Data Environment
• NIHR Health Informatics Collaborative
• NHS Data for R&D Programme
• NIHR Oxford BRC Translational Data Science
• EPSRC Centre for Doctoral Training in Healthcare Data Science 

Professor Ly-Mee Yu

Nuffield Department of Primary Care Health Sciences

• Clinical Trials Methodology
• Biostatistics

• PANORAMIC - end date March 2025
• OPTIMISE 2 - end date September 2027