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A variant form of Creutzfeldt-Jakob disease (vCJD) has had major impact in Europe during the last decade. In this article, we review the aetiology of vCJD and its relation with bovine spongiform encephalopathy. Further, treatment of the disease, the strategies focusing on prevention of transmission, future prospects, and the limitations encountered in epidemiological research of vCJD are discussed.

Original publication

DOI

10.1023/a:1024683119263

Type

Journal article

Journal

European journal of epidemiology

Publication Date

01/2003

Volume

18

Pages

473 - 477

Addresses

Genetic Epidemiology Unit, Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands. e.croes@erasmusmc.nl

Keywords

Animals, Cattle, Humans, Creutzfeldt-Jakob Syndrome, Encephalopathy, Bovine Spongiform, Europe