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The genetic structure of human populations is important in population genetics, forensics and medicine. Using genome-wide scans and individuals with all four grandparents born in the same settlement, we here demonstrate remarkable geographical structure across 8-30  km in three different parts of rural Europe. After excluding close kin and inbreeding, village of origin could still be predicted correctly on the basis of genetic data for 89-100% of individuals.

Original publication

DOI

10.1038/ejhg.2010.92

Type

Journal article

Journal

European journal of human genetics : EJHG

Publication Date

11/2010

Volume

18

Pages

1269 - 1270

Addresses

Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin, Ireland.

Keywords

Humans, Genetics, Population, Polymorphism, Single Nucleotide, Genome, Human, Principal Component Analysis, Models, Genetic, Family Health, Rural Population, Europe