Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Non-rigid image registration is widely used in the analysis of brain images to the extent it is provided as a standard tool in common packages such as SPM. However the performance of algorithms in specific applications remains hard to measure. In this paper a detailed comparison of the performance of an affine, B-Spline control-point and viscous fluid registration algorithm in inter-subject brain registration is presented. The comparison makes use of highly detailed expert manual labellings of a range of structures distributed in scale and in location in the brain. The overall performance is B-Spline, fluid, affine (best first) with all algorithms struggling to improve the match of smaller structures. We discuss caveats, evaluation strategies for registration and implications for future registration-based neuroimaging studies. © Springer-Verlag Berlin Heidelberg 2004.


Conference paper

Publication Date





679 - 686