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Picture of a large group of people on a street

A team of mathematical modellers and epidemiologists at Oxford University’s Nuffield
Department of Medicine release the latest model of a population responding to the coronavirus
epidemic. The model - OpenABM-Covid19 - provides public health decision-makers with the
ability to review the potential progression and outcome of the coronavirus, including fluctuations
in infected individuals, hospitalisations, intensive care unit (ICU) admissions and deaths, and
assess the impact of test and trace programmes.

OpenABM-Covid19 supports public health services, including the UK’s NHS England and NHS
Wales, to forecast the epidemic and decide on the best balance and scale of epidemic control
interventions over the coming months. Modelled interventions include digital contact tracing
(exposure notification system), testing, ongoing physical distancing, self-isolation, mask wearing
and further localised or national lockdown measures.

Ming Tang, Director of Data and Analytics at NHS England and NHS Improvement, says:
“Essential NHS services have been available throughout the pandemic, and this open-source
model from Oxford University is providing the NHS in England with yet another tool to help
understand potential demand on hospital services across the country, and ensure we can
continue to offer care to patients and anyone concerned about worrying symptoms.”
The UK’s latest demographic and coronavirus data feed into the model, providing a tool which is
fast, adjustable and scalable and can be updated with any country or regional demographic data
and contact networks. Infectious individuals are not randomly spread throughout a population,
and the networks on which they interact have a profound effect on the dynamics of the epidemic
and the final number of people infected. Various sized populations are modeled using real world
interactions - each person with routine and random encounters in settings such the workplace,
with family and friends, at school or university. The severity of the disease, including the
probability of hospitalisation and death, increases with age. Higher levels of transmission within
households, and mild or asymptomatic individuals, are also factored into the simulations.

Professor Christophe Fraser, scientific advisor to the Department of Health & Social Care and
Group Leader in Pathogen Dynamics at Oxford University’s Nuffield Department of Medicine,
explains, “The fact that COVID-19 affects different population groups, and that we live and
interact in distinct ways, needs to be integrated into our understanding of the potential effect of
different public health measures. The UK and other national governments are adjusting our
Oxford model to evolving policy scenarios, new measures and the latest scientific evidence. Our
model supports decision making as countries ease or scale-up policies as the epidemic
continues to evolve and as we try to return to the workplace, school, visit friends and family, and
consider how to manage safe social activities.”

The Oxford team is also supporting the development and deployment of digital contact tracing.
As apps and exposure notification systems are tested and rolled out in different countries,
the model can be adjusted to see the impact of notifying contacts based on different test result
timing and digital contact tracing configurations, such as community-level testing or not, or
change configurations to respond to adjusted guidance on self-isolation duration. The model
helps to gauge the number of tests required with different notification approaches, allowing for
testing delays or surges in incidence.

Professor Mark Briers, Programme Director at The Alan Turing Institute and Department of
Health & Social Care advisor says, " OpenABM-Covid19 has been instrumental in helping us to
understand the potential implications of the contact tracing app as a non-pharmaceutical
intervention, providing a scientific basis for the exploration of relevant policy options. Scientists
at Oxford University’s Nuffield Department of Medicine have provided continual expert scientific
advice, delivering significant impact to the UK, helping to reduce the negative health
consequences and societal implications of COVID-19.”

Dr David Bonsall, advisor to the Department of Health & Social Care, clinician and senior
researcher at Oxford University’s Nuffield Department of Medicine, adds, “We need the best
data and latest analyses to retain control of COVID-19. Our epidemic model can be updated to
ensure we optimise the speed and effectiveness of contact tracing and testing. Contact tracing
apps / Exposure notification systems should be introduced alongside other fast and effective
disease control measures to help save lives, protect people, reduce the need for widespread
lockdowns and enable us to return to more normal activities.”

The model supports public health decision-makers anywhere in the world to look at the
progression and outcome of infection and how different measures affect the population. It also
demonstrates the impact of policy decisions on people’s lives and health systems, including the
number of people in quarantine. The model has been further enhanced in partnership with
Google Research , including studies to assess the uptake needed for Exposure Notification
Systems (contact tracing apps) in the USA. Thanks to the Python interface for the model,
developed in close collaboration with the IBM UK team , it can be used and adapted by others.
Dr Nicole Mather, Life Sciences Lead at IBM UK Services, explains, “IBM UK developed the
Python interface which allows the OpenABM-Covid19 to be run by third parties. It has allowed
public health authorities to use the model not only for digital contact tracing development, but
also to support resource management and epidemic response planning for health services and
other institutions. It has been important to enable a wider range of contributors to aid the
building of OpenABM-Covid19 - we are delighted to help broaden access to this model.”

Craiger Solomons, Technical Advisory Cell for the Welsh Government explains, “ We’ve adapted
the Oxford University model to reflect the impact of COVID-19 on Wales. With support from the
team at Oxford University, the Welsh Government has integrated Welsh data and considered
different policy scenarios based on the differing contact ratios; including random, workplace and
school interactions. These data were not available for Wales previously, they’re now informing
the evidence base used by Welsh Ministers to consider national and local policy actions.”

Dr Robert Hinch, first co-author of the paper and senior researcher at Oxford University’s
Nuffield Department of Medicine, concludes, “Our Oxford model can be adjusted to other
coronavirus epidemic settings. Digital exposure notification systems based on the Google-Apple
API are being developed in many countries across Europe, Africa and in the US. It is critical that
we have the ability to analyse the possible effects of different public health interventions using
national or regional-specific demographic and contact network data. We hope this model will
continue to contribute to our response options now, and strengthen our preparedness efforts for
future pandemics.”