Research groups
Thomas Littlejohns
BSc, MSc, PhD
Senior Epidemiologist
I joined the Translational Epidemiology Unit (TEU) in 2021 to work as a senior epidemiologist. My main area of interest is investigating risk factors for dementia, with a particular focus on research that produces translatable findings with a public health benefit. This includes identifying modifiable factors that can be potentially targeted for dementia prevention.
I am also involved in research which addresses similar questions for non-dementia outcomes, in particular cancer, cardiovascular disease and other common chronic diseases.
I primarily use the UK Biobank dataset, a population-based cohort of half a million participants with a diversity of phenotypic and genetic data measured. I am also interested in using other cohorts to either replicate or complement analyses conducted using UK Biobank.
I am a module lead for the Principles of Epidemiology module as part of the MSc in Global Health Science and Epidemiology.
Before joining the TEU, I worked as an epidemiologist for the Nuffield Department of Population Health (NDPH)-based UK Biobank scientific team between 2014-2021. Prior to joining NDPH, I completed a PhD at the University of Exeter on hormonal risk factors for late-onset dementia.
Recent publications
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A foundation model for generalizable disease detection from retinal images.
Journal article
Zhou Y. et al, (2023), Nature
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Association between metabolic syndrome and risk of incident dementia in UK Biobank.
Journal article
Qureshi D. et al, (2023), Alzheimer's & dementia : the journal of the Alzheimer's Association
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Frailty and other factors associated with early outcomes in middle-to older age trauma patients: A prospective cohort study
Journal article
Yeh T-S. et al, (2023), The American Journal of Geriatric Psychiatry
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Associations of inner retinal layers with risk of incident dementia: An individual participant data analysis of four prospective cohort studies
Journal article
van der Heide FCT. et al, (2023), Alzheimer's & Dementia
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Association Between Retinal Nerve Fiber Layer Thickness and Incident Dementia in the European Prospective Investigation into Cancer in Norfolk Cohort.
Journal article
Yin GS. et al, (2023), Journal of Alzheimer's disease : JAD