BSc, MSc, PhD
I joined the Translational Epidemiology Unit (TEU) in 2021 to work as a senior epidemiologist. My main area of interest is investigating risk factors for dementia, with a particular focus on research that produces translatable findings with a public health benefit. This includes identifying modifiable factors that can be potentially targeted for dementia prevention.
I am also involved in research which addresses similar questions for non-dementia outcomes, in particular cancer, cardiovascular disease and other common chronic diseases.
I primarily use the UK Biobank dataset, a population-based cohort of half a million participants with a diversity of phenotypic and genetic data measured. I am also interested in using other cohorts to either replicate or complement analyses conducted using UK Biobank.
I am a module lead for the Principles of Epidemiology module as part of the MSc in Global Health Science and Epidemiology.
Before joining the TEU, I worked as an epidemiologist for the Nuffield Department of Population Health (NDPH)-based UK Biobank scientific team between 2014-2021. Prior to joining NDPH, I completed a PhD at the University of Exeter on hormonal risk factors for late-onset dementia.
Polygenic Risk of Prediabetes, Undiagnosed Diabetes, and Incident Type 2 Diabetes Stratified by Diabetes Risk Factors.
Liu X. et al, (2023), J Endocr Soc, 7
Association between Coeliac disease and Cardiovascular Disease: A prospective analysis in UK Biobank
CONROY M. et al, (2023), BMJ Medicine
Association of Multimorbidity, Disease Clusters, and Modification by Genetic Factors With Risk of Dementia.
Calvin CM. et al, (2022), JAMA network open, 5
Multimorbidity and risk of incident dementia: role of disease clusters and genetic risk for dementia in a cohort of 206,960 participants
LITTLEJOHNS T. et al, (2022), JAMA Network Open
Assessing agreement between different polygenic risk scores in the UK Biobank.
Clifton L. et al, (2022), Scientific reports, 12