Thomas Littlejohns
BSc, MSc, PhD
Senior Epidemiologist
I joined the Translational Epidemiology Unit (TEU) in 2021 to work as a senior epidemiologist. My main area of interest is investigating risk factors for dementia, with a particular focus on research that produces translatable findings with a public health benefit. This includes identifying modifiable factors that can be potentially targeted for dementia prevention.
I am also involved in research which addresses similar questions for non-dementia outcomes, in particular cancer, cardiovascular disease and other common chronic diseases.
I primarily use the UK Biobank dataset, a population-based cohort of half a million participants with a diversity of phenotypic and genetic data measured. I am also interested in using other cohorts to either replicate or complement analyses conducted using UK Biobank.
I am a module lead for the Principles of Epidemiology module as part of the MSc in Global Health Science and Epidemiology.
Before joining the TEU, I worked as an epidemiologist for the Nuffield Department of Population Health (NDPH)-based UK Biobank scientific team between 2014-2021. Prior to joining NDPH, I completed a PhD at the University of Exeter on hormonal risk factors for late-onset dementia.
Recent publications
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Cardiometabolic multimorbidity, genetic risk, and dementia: a prospective cohort study.
Journal article
Tai XY. et al, (2022), The Lancet. Healthy longevity, 3, e428 - e436
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Hypertension, a dementia polygenic risk score, APOE genotype, and incident dementia.
Journal article
Littlejohns TJ. et al, (2022), Alzheimer's & dementia : the journal of the Alzheimer's Association
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Identification of host-pathogen-disease relationships using a scalable Multiplex Serology platform in UK Biobank
Journal article
MENTZER A. et al, (2022), Nature Communications
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Visual impairment and risk of dementia in two population-based prospective cohorts: UK Biobank and EPIC-Norfolk
Journal article
LITTLEJOHNS T. and CONROY M., (2021), Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences
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Effects of Within-Person Variability in Spot Urinary Sodium Measurements on Associations With Blood Pressure and Cardiovascular Disease
Journal article
Re F. et al, (2021), Hypertension