Thomas Littlejohns
BSc, MSc, PhD
Senior Epidemiologist
Thomas is a module lead for the Principles of Epidemiology module as part of the MSc in Global Health Science and Epidemiology.
He joined the Translational Epidemiology Unit (TEU) in 2021 to work as a senior epidemiologist. His main area of interest is investigating risk factors for dementia, with a particular focus on research that produces translatable findings with a public health benefit. This includes identifying modifiable factors that can be potentially targeted for dementia prevention.
Thomas is also involved in research which addresses similar questions for non-dementia outcomes, in particular, cancer, cardiovascular disease and other common chronic diseases.
He primarily uses the UK Biobank dataset, a population-based cohort of half a million participants with a diversity of phenotypic and genetic data measured. Thomas is also interested in using other cohorts to either replicate or complement analyses conducted using UK Biobank.
Before joining TEU, Thomas worked as an epidemiologist for Oxford Population Health-based UK Biobank scientific team between 2014-2021. Prior to joining the department, he completed a PhD at the University of Exeter on hormonal risk factors for late-onset dementia.
Recent publications
ssociations between disease-specific polygenic risk scores and disease-specific causes of death in the UK Biobank cohort
Preprint
Liu W. et al, (2025)
Public Health.
Journal article
Gao Y. et al, (2025), Alzheimer's & dementia : the journal of the Alzheimer's Association, 21 Suppl 6
Public Health.
Journal article
Gao Y. et al, (2025), Alzheimer's & dementia : the journal of the Alzheimer's Association, 21 Suppl 6
ssociation between neuroticism and brain-wide structural outcomes: Mediation by vascular and mental conditions.
Journal article
Gao Y. et al, (2025), Psychological medicine, 55
Neuroticism, omega-3 fatty acids, and risk of incident dementia.
Journal article
Gao Y. et al, (2025), Journal of affective disorders, 388