Dr Penny Hancock
Senior Postdoctoral Researcher in Geospatial Modelling
I am interested in the ecology and evolution of mosquito-borne disease systems, with applications to mosquito control techniques. As part of the Malaria Atlas Project (MAP) team I am performing spatial analysis of the dynamics and spread of insecticide resistance in Anopheles mosquito vectors of malaria across Africa. This research interprets spatial datasets of insecticide resistance observations (representing phenotypic and genetic information) using a combination of geostatistical and machine learning approaches. The models are informed by a suite of environmental predictor variables.
I also research novel mosquito control strategies involving field releases of Wolbachia bacteria, aimed at Aedes mosquito species that vector the dengue and Zika viruses. I am developing mechanistic models of the spread of Wolbachia infections through field mosquito populations, focussing on representing patterns of spatial and demographic heterogeneity that occur in nature. Animations showing simulated patterns of spatial spread of Wolbachia following releases can be seen here: https://appliedecologistsblog.com/2019/07/10/the-amorphous-heterogeneous-spatial-spread-of-wolbachia/
Analysis-ready datasets for insecticide resistance phenotype and genotype frequency in African malaria vectors
MOYES C. et al, (2019), Scientific Data
Predicting the spatial dynamics of Wolbachia infections in Aedes aegypti arbovirus vector populations in heterogeneous landscapes
Hancock PA. et al, (2019), Journal of Applied Ecology
Associated patterns of insecticide resistance in field populations of malaria vectors across Africa.
Hancock PA. et al, (2018), Proceedings of the National Academy of Sciences of the United States of America, 115, 5938 - 5943
Predicting Wolbachia invasion dynamics in Aedes aegypti populations using models of density-dependent demographic traits.
Hancock PA. et al, (2016), BMC biology, 14
Density-dependent population dynamics Aedes aegypti slow the spread of Wmel Wolbachia
Godfray HCJ. et al, (2016), Journal of Applied Ecology