Statistical Programmer and DPhil Student
Jennifer joined the Translational Epidemiology Unit (TEU) in the Nuffield Department of Population Health (NDPH) in September 2019, where she is using UK Biobank data to investigate the performance of polygenic risk scores for common diseases. Since 2021, Jennifer is studying for a part-time DPhil in Population Health under the supervision of Professor David Hunter and Professor Gillian Reeves.
She has an MSc in Medical Statistics from the University of Leicester with a 3-month project on the use of flexible parametric models in multistate modelling, and an MMath from Durham University, where her final project was on interacting particle systems and their use in modelling the spread of epidemics.
Jennifer has a longstanding interest in the applications of maths and statistics to medicine; throughout her 4-year MMath she spent holidays doing temp work for MBRRACE-UK in the National Perinatal Epidemiology Unit (NPEU).
Are polygenic risk scores for systolic blood pressure and LDL-cholesterol associated with treatment effectiveness, and clinical outcomes among those on treatment?
Tapela NM. et al, (2022), European journal of preventive cardiology, 29, 925 - 937
Hypertension, a dementia polygenic risk score, APOE genotype, and incident dementia.
Littlejohns TJ. et al, (2022), Alzheimer's & dementia : the journal of the Alzheimer's Association
Calculating Polygenic Risk Scores (PRS) in UK Biobank: A Practical Guide for Epidemiologists.
Collister JA. et al, (2022), Frontiers in genetics, 13