Evan Irving-Pease
Group Leader and Royal Society University Research Fellow
Evan is a Group Leader at the Big Data Institute and Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford. His research focuses on understanding the patterns and processes of natural selection, and the role played by environmental factors (e.g., human culture, infectious disease, climate change and ecosystem dynamics) in shaping phenotypic diversity and driving episodes of rapid polygenic adaptation in human and animal populations.
Research Interests:
Palaeogenomics, Ancient DNA, Natural Selection, Complex Traits, Domestication, Pathogens
Key publications
-
Tracing the evolutionary history of the CCR5delta32 deletion via ancient and modern genomes.
Journal article
Ravn K. et al, (2025), Cell, 188, 3679 - 3695.e16
-
The selection landscape and genetic legacy of ancient Eurasians.
Journal article
Irving-Pease EK. et al, (2024), Nature, 625, 312 - 320
-
Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations.
Journal article
Barrie W. et al, (2024), Nature, 625, 321 - 328
-
Ancient DNA reveals evolutionary origins of autoimmune diseases.
Journal article
Barrie W. et al, (2024), Nature reviews. Immunology, 24, 85 - 86
Recent publications
-
Imputation of ancient canid genomes reveals inbreeding history over the past 10,000 years.
Journal article
Bougiouri K. et al, (2025), Proceedings of the National Academy of Sciences of the United States of America, 122
-
Multivariate genome-wide association analysis of dyslexia and quantitative reading skill improves gene discovery.
Journal article
Mountford HS. et al, (2025), Translational psychiatry, 15
-
The spatiotemporal distribution of human pathogens in ancient Eurasia.
Journal article
Sikora M. et al, (2025), Nature, 643, 1011 - 1019
-
Tracing the evolutionary history of the CCR5delta32 deletion via ancient and modern genomes.
Journal article
Ravn K. et al, (2025), Cell, 188, 3679 - 3695.e16
-
Ancient DNA reveals evolutionary origins of autoimmune diseases.
Journal article
Barrie W. et al, (2024), Nature reviews. Immunology, 24, 85 - 86