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Dr Evan Irving-Pease

Dr Evan Irving-Pease

Evan Irving-Pease

Group Leader and Royal Society University Research Fellow

Evan is a Group Leader at the Big Data Institute and Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford. His research focuses on understanding the patterns and processes of natural selection, and the role played by environmental factors (e.g., human culture, infectious disease, climate change and ecosystem dynamics) in shaping phenotypic diversity and driving episodes of rapid polygenic adaptation in human and animal populations.

Research Interests:
Palaeogenomics, Ancient DNA, Natural Selection, Complex Traits, Domestication, Pathogens

Key publications

Tracing the evolutionary history of the CCR5delta32 deletion via ancient and modern genomes.

Journal article

Ravn K. et al, (2025), Cell, 188, 3679 - 3695.e16

Ancient DNA reveals evolutionary origins of autoimmune diseases.

Journal article

Barrie W. et al, (2024), Nature reviews. Immunology, 24, 85 - 86

The selection landscape and genetic legacy of ancient Eurasians.

Journal article

Irving-Pease EK. et al, (2024), Nature, 625, 312 - 320

Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations.

Journal article

Barrie W. et al, (2024), Nature, 625, 321 - 328

Recent publications

Imputation of ancient canid genomes reveals inbreeding history over the past 10,000 years.

Journal article

Bougiouri K. et al, (2025), Proceedings of the National Academy of Sciences of the United States of America, 122

Multivariate genome-wide association analysis of dyslexia and quantitative reading skill improves gene discovery.

Journal article

Mountford HS. et al, (2025), Translational psychiatry, 15

The spatiotemporal distribution of human pathogens in ancient Eurasia.

Journal article

Sikora M. et al, (2025), Nature, 643, 1011 - 1019

Tracing the evolutionary history of the CCR5delta32 deletion via ancient and modern genomes.

Journal article

Ravn K. et al, (2025), Cell, 188, 3679 - 3695.e16

Ancient DNA reveals evolutionary origins of autoimmune diseases.

Journal article

Barrie W. et al, (2024), Nature reviews. Immunology, 24, 85 - 86

More publications