We investigated the relationship between individual subjects' functional connectomes and 280 behavioral and demographic measures in a single holistic multivariate analysis relating imaging to non-imaging data from 461 subjects in the Human Connectome Project. We identified one strong mode of population co-variation: subjects were predominantly spread along a single 'positive-negative' axis linking lifestyle, demographic and psychometric measures to each other and to a specific pattern of brain connectivity.

Original publication

DOI

10.1038/nn.4125

Type

Journal article

Journal

Nat Neurosci

Publication Date

11/2015

Volume

18

Pages

1565 - 1567

Keywords

Adult, Behavior, Brain, Cluster Analysis, Connectome, Demography, Female, Humans, Magnetic Resonance Imaging, Male, Models, Neurological, Nerve Net, Young Adult