We investigated the relationship between individual subjects' functional connectomes and 280 behavioral and demographic measures in a single holistic multivariate analysis relating imaging to non-imaging data from 461 subjects in the Human Connectome Project. We identified one strong mode of population co-variation: subjects were predominantly spread along a single 'positive-negative' axis linking lifestyle, demographic and psychometric measures to each other and to a specific pattern of brain connectivity.

Original publication

DOI

10.1038/nn.4125

Type

Journal article

Journal

Nature neuroscience

Publication Date

11/2015

Volume

18

Pages

1565 - 1567

Addresses

Oxford University Centre for Functional MRI of the Brain (FMRIB), Oxford, UK.

Keywords

Brain, Nerve Net, Humans, Magnetic Resonance Imaging, Cluster Analysis, Behavior, Demography, Models, Neurological, Adult, Female, Male, Young Adult, Connectome