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To use crystallography for the determination of the three-dimensional structures of proteins, protein crystals need to be grown. Automated imaging systems are increasingly being used to monitor these crystallization experiments. These present problems of accessibility to the data, repeatability of any image analysis performed and the amount of storage required. Various image formats and techniques can be combined to provide effective solutions to high volume processing problems such as these, however lack of widespread support for the most effective algorithms, such as JPeg2000 which yielded a 64% improvement in file size over the bitmap, currently inhibits the immediate take up of this approach.

Original publication

DOI

10.1142/s0129065705000384

Type

Journal article

Journal

International journal of neural systems

Publication Date

12/2005

Volume

15

Pages

415 - 425

Addresses

Division of Structural Biology, University of Oxford, Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford, OX3 7BN, UK. ian@strubi.ox.ac.uk

Keywords

Imaging, Three-Dimensional, Crystallization, Crystallography, Protein Structure, Tertiary, Algorithms, Image Processing, Computer-Assisted, Software