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Linear regression analysis was used to compare penicillin MICs determined with 3,129 recent clinical isolates of Streptococcus pneumoniae to MICs obtained with nine other beta-lactam antimicrobial agents. A strong correlation between penicillin MICs and those obtained with other beta-lactams was demonstrated. It may be possible to test penicillin and use MICs obtained with penicillin to predict MICs of other beta-lactam antimicrobials for Streptococcus pneumoniae.

Original publication

DOI

10.1128/JCM.39.1.367-369.2001

Type

Journal article

Journal

Journal of clinical microbiology

Publication Date

01/2001

Volume

39

Pages

367 - 369

Addresses

Medical Microbiology Division, Department of Pathology, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA.

Keywords

Humans, Streptococcus pneumoniae, Pneumococcal Infections, beta-Lactams, Penicillins, Anti-Bacterial Agents, Microbial Sensitivity Tests, Linear Models, Predictive Value of Tests