This paper reviews the developments in high-throughput and nanolitre-scale protein crystallography technologies within the remit of workpackage 4 of the Structural Proteomics In Europe (SPINE) project since the project's inception in October 2002. By surveying the uptake, use and experience of new technologies by SPINE partners across Europe, a picture emerges of highly successful adoption of novel working methods revolutionizing this area of structural biology. Finally, a forward view is taken of how crystallization methodologies may develop in the future.

Original publication

DOI

10.1107/S090744490602943X

Type

Journal article

Journal

Acta Crystallogr D Biol Crystallogr

Publication Date

10/2006

Volume

62

Pages

1137 - 1149

Keywords

Crystallography, Image Processing, Computer-Assisted, Nanotechnology, Plastics, Proteins, Proteomics, Quality Control, Robotics