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Heart failure remains a major cause of morbidity and mortality despite optimum treatment with angiotensin-converting enzyme inhibitors and diuretics. Meta-analysis of recent placebo-controlled, randomized trials suggest that treatment with beta-blockers may significantly reduce mortality by 35%.

Original publication

DOI

10.1046/j.1365-2710.1997.9775097.x

Type

Journal article

Journal

Journal of clinical pharmacy and therapeutics

Publication Date

06/1997

Volume

22

Pages

181 - 185

Addresses

Department of Medicine, University of Birmingham, Queen Elizabeth Hospital, Edgbaston, U.K.

Keywords

Humans, Adrenergic beta-Antagonists, Angiotensin-Converting Enzyme Inhibitors, Follow-Up Studies, Down-Regulation, Blood Pressure, Heart Rate, Myocardial Contraction, Heart Failure, Randomized Controlled Trials as Topic