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The techniques used in protein production and structural biology have been developing rapidly, but techniques for recording the laboratory information produced have not kept pace. One approach is the development of laboratory information-management systems (LIMS), which typically use a relational database schema to model and store results from a laboratory workflow. The underlying philosophy and implementation of the Protein Information Management System (PiMS), a LIMS development specifically targeted at the flexible and unpredictable workflows of protein-production research laboratories of all scales, is described. PiMS is a web-based Java application that uses either Postgres or Oracle as the underlying relational database-management system. PiMS is available under a free licence to all academic laboratories either for local installation or for use as a managed service.

Original publication

DOI

10.1107/s0907444911007943

Type

Journal article

Journal

Acta crystallographica. Section D, Biological crystallography

Publication Date

04/2011

Volume

67

Pages

249 - 260

Addresses

CSED, STFC Daresbury Laboratory, Warrington, England.

Keywords

Proteins, Databases, Protein, Management Information Systems