Variation in brain structure may reflect variation in functional properties of specific brain systems. Structural variation may therefore reflect variation in behavioural performance. Here, we use diffusion-weighted magnetic resonance imaging to show that variation in white matter integrity in a specific region in the body of the corpus callosum is associated with variation in performance of a bimanual co-ordination task. When the callosal region showing this association is used as a seed for probabilistic tractography, inter-hemispheric pathways are generated to the supplementary motor area and caudal cingulate motor area. This provides further evidence for the role of medial wall motor areas in bimanual co-ordination and supports the idea that variation in brain structure reflects inter-individual differences in skilled performance.

Original publication

DOI

10.1016/j.neuroimage.2007.03.041

Type

Journal article

Journal

Neuroimage

Publication Date

2007

Volume

36 Suppl 2

Pages

T16 - T21

Keywords

Adult, Anisotropy, Brain Mapping, Corpus Callosum, Diffusion Magnetic Resonance Imaging, Female, Functional Laterality, Humans, Male, Middle Aged, Psychomotor Performance