Variation in brain structure may reflect variation in functional properties of specific brain systems. Structural variation may therefore reflect variation in behavioural performance. Here, we use diffusion-weighted magnetic resonance imaging to show that variation in white matter integrity in a specific region in the body of the corpus callosum is associated with variation in performance of a bimanual co-ordination task. When the callosal region showing this association is used as a seed for probabilistic tractography, inter-hemispheric pathways are generated to the supplementary motor area and caudal cingulate motor area. This provides further evidence for the role of medial wall motor areas in bimanual co-ordination and supports the idea that variation in brain structure reflects inter-individual differences in skilled performance.

Original publication

DOI

10.1016/j.neuroimage.2007.03.041

Type

Journal article

Journal

NeuroImage

Publication Date

01/2007

Volume

36 Suppl 2

Pages

T16 - T21

Addresses

Oxford Centre for Functional MRI of the Brain, John Radcliffe Hospital, Headington, Oxford, OX3 0HS, UK. heidi@fmrib.ox.ac.uk

Keywords

Corpus Callosum, Humans, Diffusion Magnetic Resonance Imaging, Brain Mapping, Psychomotor Performance, Anisotropy, Adult, Middle Aged, Female, Male, Functional Laterality