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We revisit a previous study on inter-session variability (McGonigle et al. [2000]: Neuroimage 11:708-734), showing that contrary to one popular interpretation of the original article, inter-session variability is not necessarily high. We also highlight how evaluating variability based on thresholded single-session images alone can be misleading. Finally, we show that the use of different first-level preprocessing, time-series statistics, and registration analysis methodologies can give significantly different inter-session analysis results.

Original publication

DOI

10.1002/hbm.20080

Type

Journal article

Journal

Human brain mapping

Publication Date

03/2005

Volume

24

Pages

248 - 257

Addresses

Oxford Centre for Functional Magnetic Resonance Imaging of the Brain (FMRIB), Department of Clinical Neurology, Oxford University, John Radcliffe Hospital, Headington, Oxford, United Kingdom. steve@fmrib.ox.ac.uk

Keywords

Brain, Humans, Magnetic Resonance Imaging, Artifacts, Brain Mapping, Reproducibility of Results, Head Movements, Image Processing, Computer-Assisted, Adult, Male