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BackgroundThe European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for the Prevention of Allergic Disease. We seek to critically assess the effectiveness, cost-effectiveness, and safety of AIT in the prevention of allergic disease.MethodsWe will undertake a systematic review, which will involve searching international biomedical databases for published, in progress and unpublished evidence. Studies will be independently screened against pre-defined eligibility criteria and critically appraised using established instruments. Data will be descriptively and, if possible and appropriate, quantitatively synthesized.DiscussionThe findings from this review will be used to inform the development of recommendations for EAACI's Guidelines on AIT.

Original publication

DOI

10.1111/pai.12524

Type

Journal article

Journal

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology

Publication Date

05/2016

Volume

27

Pages

236 - 241

Addresses

Evidence-Based Health Care Ltd, Edinburgh, UK.

Keywords

Humans, Hypersensitivity, Desensitization, Immunologic, European Union, Databases, Factual, Cost-Benefit Analysis, Academies and Institutes, Review Literature as Topic, Practice Guidelines as Topic, Systematic Reviews as Topic