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Anaphylaxis is a life-threatening emergency that appears to be increasing in frequency. It affects males and females of all ages and ethnic groups. The most common triggers include foods, drugs and venom from stinging insects, although any of a number of other triggers may also be implicated. Death, when it occurs, tends to be due to respiratory and/or cardiovascular compromise, but most of these fatalities can be prevented by appropriate avoidance measures and emergency management. The management of anaphylaxis is hampered by scientific and clinical uncertainty.

Original publication

DOI

10.1586/eci.09.73

Type

Journal article

Journal

Expert review of clinical immunology

Publication Date

01/2010

Volume

6

Pages

89 - 100

Addresses

Centre for Population Health Sciences, General Practice Section, University of Edinburgh, 20 West Richmond Street, Edinburgh EH8 9DX, UK. allison.worth@ed.ac.uk

Keywords

Humans, Anaphylaxis, Epinephrine, Histamine Antagonists, Glucocorticoids, Treatment Outcome, Clinical Protocols, Combined Modality Therapy, Fluid Therapy, Emergency Treatment, Oxygen Inhalation Therapy, Algorithms, Female, Male, Terminology as Topic, Practice Guidelines as Topic, Patient Positioning