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Search results (562)

« Back to Publications

From GWAS to drug: A framework for drug candidate prioritisation using a gene expression signature matching approach

Chauquet S. et al, (2026)

Rethinking covariate adjustment in psychiatric biomarker research: a framework applied to UK Biobank blood samples

Shin M. et al, (2026)

Genome-wide meta-analyses of non-response to antidepressants provide insights into underlying molecular genetics and suggest potential pharmacotherapies.

Koch E. et al, (2026), Molecular psychiatry, 31, 2005 - 2013

Psychiatric Nosology Should Include Genetic Syndromes.

Wray NR. and Owen MJ., (2026), Biological psychiatry, 99, 508 - 510

Progress in understanding the biological basis of polygenic disorders.

Wray NR. et al, (2026), Current opinion in genetics & development, 97

Genetic and Phenotypic Associations With Sustained Antidepressant Use in Major Depressive Disorder.

Walker A. et al, (2026), JAMA psychiatry, 83, 247 - 258

Phenome-Wide Associations of Polygenic Scores for Schizophrenia and Major Depression in 100,000 Chinese Adults.

Wang B. et al, (2026), Biological psychiatry global open science, 6

Genome-wide fine-mapping improves identification of causal variants.

Wu Y. et al, (2026), Nature genetics

Cohort Profile: Investigating Antidepressant Response within Generation Scotland

Calnan M. et al, (2026)

Multi-ancestry conditional and joint analysis (Manc-COJO) applied to GWAS summary statistics

Wang X. et al, (2026)

Effects of 6-months of SSRI use on DNA-methylation and gene expression in blood.

Barker LF. et al, (2026), Brain, behavior, and immunity, 135

Applying machine-learning and deep-learning to predict depression from brain MRI and identify depression-related brain biology.

Jiang J-C. et al, (2026), Translational psychiatry, 16

Large-scale drug screening in iPSC-derived motor neurons from sporadic ALS patients identifies a potential combinatorial therapy.

Bye CR. et al, (2026), Nature neuroscience, 29, 40 - 52

Atypical Depression Is Associated With a Distinct Clinical, Neurobiological, Treatment Response, and Polygenic Risk Profile.

Shin M. et al, (2026), Biological psychiatry

Mapping the genetic landscape across 14 psychiatric disorders.

Grotzinger AD. et al, (2026), Nature, 649, 406 - 415

Genomic risk prediction for depression in a large prospective study of older adults of European descent.

Yu C. et al, (2025), Molecular psychiatry, 30, 5865 - 5872

Integrating Multi-Omics Summary Data Identifies Candidate Molecular Mechanisms for Major Depression.

Nisbet L. et al, (2025), Biological psychiatry

Population-representative inference for primary and secondary outcomes in extended case-cohort designs

Wimberley T. et al, (2025), Discover Public Health, 22

From variants to mechanisms: Neurogenomics in the post-GWAS era.

Margolis MP. et al, (2025), Neuron, 113, 3509 - 3529

Epigenetic profiles of tissue informative CpGs inform ALS disease status and progression.

Caggiano C. et al, (2025), Genome medicine, 17

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