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This report describes 12 Dutch families of which at least two members have had Guillain-Barre syndrome (GBS). The authors observed an earlier onset of GBS in successive generations. The occurrence of GBS within families suggests a role for genetic factors in the pathogenesis of GBS.

Original publication

DOI

10.1212/01.wnl.0000143055.09646.31

Type

Journal article

Journal

Neurology

Publication Date

11/2004

Volume

63

Pages

1747 - 1750

Addresses

Department of Neurology, Room Ee 2230, Erasmus Medical Center, PO Box 1738, 3000 DR Rotterdam, The Netherlands. c.geleijns@erasmusmc.nl

Keywords

Humans, Guillain-Barre Syndrome, Genetic Predisposition to Disease, Pedigree, Age of Onset, Adult, Aged, Middle Aged, Child, Child, Preschool, Infant, Newborn, Female, Male