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The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic, neurological, ophthalmic, psychiatric and respiratory diseases. As of 2008, 14,926 subjects aged 45 years or over comprise the Rotterdam Study cohort. The findings of the Rotterdam Study have been presented in close to a 1,000 research articles and reports (see www.epib.nl/rotterdamstudy). This article gives the rationale of the study and its design. It also presents a summary of the major findings and an update of the objectives and methods.

Original publication

DOI

10.1007/s10654-009-9386-z

Type

Journal article

Journal

European journal of epidemiology

Publication Date

01/2009

Volume

24

Pages

553 - 572

Addresses

Department of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam. The Netherlands. a.hofman@erasmusmc.nl

Keywords

Humans, Liver Diseases, Pulmonary Disease, Chronic Obstructive, Nervous System Diseases, Eye Diseases, Cardiovascular Diseases, Endocrine System Diseases, Chronic Disease, Cohort Studies, Prospective Studies, Mental Disorders, Genetic Research, Pharmacoepidemiology, Research Design, Aged, Middle Aged, Netherlands, Female, Male