htsget: a protocol for securely streaming genomic data.
Kelleher J., Lin M., Albach CH., Birney E., Davies R., Gourtovaia M., Glazer D., Gonzalez CY., Jackson DK., Kemp A., Marshall J., Nowak A., Senf A., Tovar-Corona JM., Vikhorev A., Keane TM., GA4GH Streaming Task Team None.
Summary:Standardized interfaces for efficiently accessing high-throughput sequencing data are a fundamental requirement for large-scale genomic data sharing. We have developed htsget, a protocol for secure, efficient and reliable access to sequencing read and variation data. We demonstrate four independent client and server implementations, and the results of a comprehensive interoperability demonstration. Availability and implementation:http://samtools.github.io/hts-specs/htsget.html. Supplementary information:Supplementary data are available at Bioinformatics online.