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Summary:Standardized interfaces for efficiently accessing high-throughput sequencing data are a fundamental requirement for large-scale genomic data sharing. We have developed htsget, a protocol for secure, efficient and reliable access to sequencing read and variation data. We demonstrate four independent client and server implementations, and the results of a comprehensive interoperability demonstration. Availability and implementation:http://samtools.github.io/hts-specs/htsget.html. Supplementary information:Supplementary data are available at Bioinformatics online.

Original publication

DOI

10.1093/bioinformatics/bty492

Type

Journal article

Journal

Bioinformatics (Oxford, England)

Publication Date

01/2019

Volume

35

Pages

119 - 121

Addresses

Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.

Keywords

GA4GH Streaming Task Team