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It is widely supposed that the tissue specificity of gene expression indicates gene function. Now, an extensive analysis of gene expression in the mouse reveals that quantitative measurement of expression levels in different tissues can contribute powerfully to the prediction of gene function.

Original publication

DOI

10.1186/jbiol19

Type

Journal article

Journal

Journal of biology

Publication Date

01/2004

Volume

3

Addresses

MRC Mammalian Genetics Unit, Harwell OX11 0RD, UK.

Keywords

Animals, Humans, Mice, Oligonucleotide Array Sequence Analysis, Gene Expression Profiling, Computational Biology, Genomics, Organ Specificity, Genes