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We consider the development of Bayesian Nonparametric methods for product partition models such as Hidden Markov Models and change point models. Our approach uses a Mixture of Dirichlet Process (MDP) model for the unknown sampling distribution (likelihood) for the observations arising in each state and a computationally efficient data augmentation scheme to aid inference. The method uses novel MCMC methodology which combines recent retrospective sampling methods with the use of slice sampler variables. The methodology is computationally efficient, both in terms of MCMC mixing properties, and robustness to the length of the time series being investigated. Moreover, the method is easy to implement requiring little or no user-interaction. We apply our methodology to the analysis of genomic copy number variation.

Original publication

DOI

10.1111/j.1467-9868.2010.00756.x

Type

Journal article

Journal

Journal of the Royal Statistical Society. Series B, Statistical methodology

Publication Date

01/2011

Volume

73

Pages

37 - 57

Addresses

Department of Statistics and the Oxford-Man Institute for Quantitative Finance, University of Oxford, yau@stats.ox.ac.uk , cholmes@stats.ox.ac.uk.