Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Accept all cookies Reject all non-essential cookies Find out more

Structural Brain Correlates of Childhood Inhibited Temperament: An ENIGMA-Anxiety Mega-analysis.

Bas-Hoogendam JM., Bernstein R., Benson BE., Buss KA., Gunther KE., Pérez-Edgar K., Salum GA., Jackowski AP., Bressan RA., Zugman A., Degnan KA., Filippi CA., Fox NA., Henderson HA., Tang A., Zeytinoglu S., Harrewijn A., Hillegers MHJ., White T., van IJzendoorn MH., Schwartz CE., Felicione JM., DeYoung KA., Shackman AJ., Smith JF., Tillman RM., van den Berg YHM., Cillessen AHN., Roelofs K., Tyborowska A., Hill SY., Battaglia M., Tettamanti M., Dougherty LR., Jin J., Klein DN., Leung H-C., Avery SN., Blackford JU., Clauss JA., Hayden EP., Liu P., Vandermeer MRJ., Goldsmith HH., Planalp EM., Nichols TE., Thompson PM., Westenberg PM., van der Wee NJA., Groenewold NA., Stein DJ., Winkler AM., Pine DS., ENIGMA-Anxiety Working Group .

Temperament involves stable behavioral and emotional tendencies that differ between individuals, which can be first observed in infancy or early childhood and relate to behavior in many contexts and over many years.1 One of the most rigorously characterized temperament classifications relates to the tendency of individuals to avoid the unfamiliar and to withdraw from unfamiliar people, objects, and unexpected events. This temperament is referred to as behavioral inhibition or inhibited temperament (IT).2 IT is a moderately heritable trait1 that can be measured in multiple species.3 In humans, levels of IT can be quantified from the first year of life through direct behavioral observations or reports by caregivers or teachers. Similar approaches as well as self-report questionnaires on current and/or retrospective levels of IT1 can be used later in life.

More information Original publication

DOI

10.1016/j.jaac.2022.04.023

Type

Journal article

Publication Date

2022-09-01T00:00:00+00:00

Volume

61

Pages

1182 - 1188

Total pages

6

Addresses

L, e, i, d, e, n, , U, n, i, v, e, r, s, i, t, y, ,, , L, e, i, d, e, n, ,, , t, h, e, , N, e, t, h, e, r, l, a, n, d, s, ;, , L, e, i, d, e, n, , U, n, i, v, e, r, s, i, t, y, , M, e, d, i, c, a, l, , C, e, n, t, e, r, ,, , L, e, i, d, e, n, ,, , t, h, e, , N, e, t, h, e, r, l, a, n, d, s, ;, , L, e, i, d, e, n, , I, n, s, t, i, t, u, t, e, , f, o, r, , B, r, a, i, n, , a, n, d, , C, o, g, n, i, t, i, o, n, ,, , L, e, i, d, e, n, ,, , t, h, e, , N, e, t, h, e, r, l, a, n, d, s, ;, , N, a, t, i, o, n, a, l, , I, n, s, t, i, t, u, t, e, , o, f, , M, e, n, t, a, l, , H, e, a, l, t, h, ,, , B, e, t, h, e, s, d, a, ,, , M, a, r, y, l, a, n, d, ., , E, l, e, c, t, r, o, n, i, c, , a, d, d, r, e, s, s, :, , j, ., m, ., h, o, o, g, e, n, d, a, m, @, f, s, w, ., l, e, i, d, e, n, u, n, i, v, ., n, l, .

Keywords

ENIGMA-Anxiety Working Group, Brain, Humans, Retrospective Studies, Anxiety, Temperament, Anxiety Disorders, Child, Preschool