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Advances in genomics and computing are transforming the capacity for the characterization of biological systems, and researchers are now poised for a precision-focused transformation in the way they prepare for, and respond to, infectious diseases. This includes the use of genome-based approaches to inform molecular diagnosis and individual-level treatment regimens. In addition, advances in the speed and granularity of pathogen genome generation have improved the capability to track and understand pathogen transmission, leading to potential improvements in the design and implementation of population-level public health interventions. In this Perspective, we outline several trends that are driving the development of precision epidemiology of infectious disease and their implications for scientists' ability to respond to outbreaks.

Original publication

DOI

10.1038/s41591-019-0345-2

Type

Journal article

Journal

Nature medicine

Publication Date

06/02/2019

Volume

25

Pages

206 - 211

Addresses

Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, AZ, USA.

Keywords

Humans, Communicable Diseases, Genomics, Disease Outbreaks, Communicable Disease Control