Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

With the widespread availability of functional magnetic resonance imaging (fMRI), there has been rapid progress in identifying neural correlates of cognition and emotion in the human brain. In conjunction with basic research studies, fMRI has been increasingly applied in clinical disorders, making it a central research tool in human psychopathology, psychopharmacology, and genetics. In the present article, we discuss a number of conceptual and methodological challenges that confront the implementation of fMRI in clinical and translational research, and we offer a set of recommendations intended to enhance the interpretability and reproducibility of results in clinical fMRI.

Original publication

DOI

10.1016/j.biopsych.2008.06.014

Type

Journal article

Journal

Biological psychiatry

Publication Date

11/2008

Volume

64

Pages

842 - 849

Addresses

Departments of Psychiatry and Psychology, University of California at Davis, Sacramento, California 95817, USA. cameron.carter@ucdmc.ucdavis.edu

Keywords

Brain, Humans, Oxygen, Image Interpretation, Computer-Assisted, Magnetic Resonance Imaging, Brain Mapping, Research Design