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Motivation:The size and complexity of modern large-scale genome variation studies demand novel approaches for exploring and sharing the data. In order to unlock the potential of these data for a broad audience of scientists with various areas of expertise, a unified exploration framework is required that is accessible, coherent and user-friendly. Results:Panoptes is an open-source software framework for collaborative visual exploration of large-scale genome variation data and associated metadata in a web browser. It relies on technology choices that allow it to operate in near real-time on very large datasets. It can be used to browse rich, hybrid content in a coherent way, and offers interactive visual analytics approaches to assist the exploration. We illustrate its application using genome variation data of Anopheles gambiae, Plasmodium falciparum and Plasmodium vivax. Availability and implementation:Freely available at https://github.com/cggh/panoptes, under the GNU Affero General Public License. Contact:paul.vauterin@gmail.com.

Original publication

DOI

10.1093/bioinformatics/btx410

Type

Journal article

Journal

Bioinformatics (Oxford, England)

Publication Date

10/2017

Volume

33

Pages

3243 - 3249

Addresses

MRC Centre for Genomics and Global Health, University of Oxford, Oxford OX3 7BN, UK.

Keywords

Animals, Anopheles, Plasmodium falciparum, Plasmodium vivax, Sequence Analysis, DNA, Genomics, Internet, Software, Genetic Variation, Web Browser, Metadata