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Motivation:The size and complexity of modern large-scale genome variation studies demand novel approaches for exploring and sharing the data. In order to unlock the potential of these data for a broad audience of scientists with various areas of expertise, a unified exploration framework is required that is accessible, coherent and user-friendly. Results:Panoptes is an open-source software framework for collaborative visual exploration of large-scale genome variation data and associated metadata in a web browser. It relies on technology choices that allow it to operate in near real-time on very large datasets. It can be used to browse rich, hybrid content in a coherent way, and offers interactive visual analytics approaches to assist the exploration. We illustrate its application using genome variation data of Anopheles gambiae, Plasmodium falciparum and Plasmodium vivax. Availability and implementation:Freely available at, under the GNU Affero General Public License.

Original publication




Journal article


Bioinformatics (Oxford, England)

Publication Date





3243 - 3249


MRC Centre for Genomics and Global Health, University of Oxford, Oxford OX3 7BN, UK.


Animals, Anopheles, Plasmodium falciparum, Plasmodium vivax, Sequence Analysis, DNA, Genomics, Internet, Software, Genetic Variation, Web Browser, Metadata