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We compared the genetic diversity of the Brazilian human T-cell lymphotropic virus type 1 isolates with those found in KwaZulu-Natal (KZN), South Africa, and with the genetic background of the hosts. The seroprevalence rate in KZN was 1.7%. All sequences belonged to the A subgroup. The presence of South African sequences in two different clusters from Brazil, and the finding of the beta-globin haplotype in infected hosts are consistent with the transmission of this virus from southern Africa to Brazil.

Original publication

DOI

10.1097/01.aids.0000216383.14808.13

Type

Journal article

Journal

AIDS (London, England)

Publication Date

03/2006

Volume

20

Pages

780 - 782

Addresses

Public Health Advanced Laboratory, Gonçalo Moniz Research Center, Oswaldo Cruz Foundation, Salvador, Bahia, Brazil.

Keywords

Humans, Human T-lymphotropic virus 1, HTLV-I Infections, Globins, Seroepidemiologic Studies, Evolution, Molecular, Phylogeny, Terminal Repeat Sequences, Haplotypes, Genes, Viral, South Africa, Brazil, Genetic Variation, Molecular Epidemiology