The interleukin-2-mediated immune response is critical for host defense against infectious pathogens. Cytokine-inducible SRC homology 2 (SH2) domain protein (CISH), a suppressor of cytokine signaling, controls interleukin-2 signaling.

Original publication

DOI

10.1056/NEJMoa0905606

Type

Journal article

Journal

The New England journal of medicine

Publication Date

06/2010

Volume

362

Pages

2092 - 101