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Septic arthritis is a rare complication of typhoid fever. A 12-year-old boy without pre-existing disease attended a paediatric hospital in Cambodia with fever and left hip pain. A hip synovial fluid aspirate grew multidrug-resistant Salmonella enterica ser. Typhi with intermediate susceptibility to ciprofloxacin. Arthrotomy, 2 weeks of intravenous ceftriaxone and 4 weeks of oral azithromycin led to resolution of symptoms. The optimum management of septic arthritis in drug-resistant typhoid is undefined.

Original publication




Journal article


Paediatrics and international child health

Publication Date





227 - 229


Hip Joint, Synovial Fluid, Humans, Salmonella typhi, Typhoid Fever, Arthritis, Infectious, Ceftriaxone, Azithromycin, Anti-Bacterial Agents, Treatment Outcome, Debridement, Microbial Sensitivity Tests, Drug Resistance, Multiple, Bacterial, Child, Cambodia, Male