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Array-based comparative genomic hybridization (CGH) technology is used to discover and validate genomic structural variation, including copy number variants, insertions, deletions and other structural variants (SVs). The visualization and summarization of the array CGH data outputs, potentially across many samples, is an important process in the identification and analysis of SVs. We have developed a software tool for SV analysis using data from array CGH technologies, which is also amenable to short-read sequence data.SnoopCGH is written in java and is available from http://snoopcgh.sourceforge.net/

Original publication

DOI

10.1093/bioinformatics/btp488

Type

Journal article

Journal

Bioinformatics (Oxford, England)

Publication Date

10/2009

Volume

25

Pages

2732 - 2733

Addresses

Wellcome Trust Sanger Institute, Hinxton, The Weatherall Institute of Molecular Medicine and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. jg10@sanger.ac.uk

Keywords

Plasmodium falciparum, Oligonucleotide Array Sequence Analysis, Gene Expression Profiling, Computational Biology, Genome, Bacterial, Genome, Computer Graphics, Software, Comparative Genomic Hybridization