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This unit introduces the concept of hidden Markov models in computational biology. It describes them using simple biological examples, requiring as little mathematical knowledge as possible. The unit also presents a brief history of hidden Markov models and an overview of their current applications before concluding with a discussion of their limitations.

Original publication

DOI

10.1002/0471250953.bia03as18

Type

Journal article

Journal

Current protocols in bioinformatics

Publication Date

06/2007

Volume

Appendix 3

Pages

Appendix - 3A

Addresses

Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom.

Keywords

Data Interpretation, Statistical, Models, Statistical, Markov Chains, Sequence Analysis, Algorithms, Models, Biological, Artificial Intelligence, Computer Simulation, Pattern Recognition, Automated