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The assumption that human mitochondrial DNA is inherited from one parent only and therefore does not recombine is questionable. Linkage disequilibrium in human and chimpanzee mitochondrial DNA declines as a function of the distance between sites. This pattern can be attributed to one mechanism only: recombination.

Original publication

DOI

10.1126/science.286.5449.2524

Type

Journal article

Journal

Science (New York, N.Y.)

Publication Date

12/1999

Volume

286

Pages

2524 - 2525

Addresses

Institute of Cell, Animal and Population Biology, University of Edinburgh, Edinburgh EH9 1JT, UK.

Keywords

Animals, Hominidae, Humans, Pan troglodytes, NADH Dehydrogenase, DNA, Mitochondrial, Fathers, Evolution, Molecular, Recombination, Genetic, Linkage Disequilibrium, Polymorphism, Restriction Fragment Length, Female, Male