Director, Big Data Institute; Professor of Statistical Genetics, Nuffield Department of Medicine
- Head of Bioinformatics and Statistical Genetics
- University Lecturer in Mathematical Genetics
- Group Head / PI and Unit Director,
My research covers several areas in the analysis of genetic variation, combining the development of methods for analysing high throughput sequencing data, theoretical work and empirical analysis. Of particular interest are: the analysis of recombination from population genetic data, dissecting signals of disease association within the HLA, methods for inferring genealogical history from DNA sequence data and de novo sequence assemblyfor the discovery of genetic variation. I am a member of the Mathematical Genetics Group in the Department of Statistics and Acting Director of the new Oxford Big Data Institute.
Inferring whole-genome histories in large population datasets.
Kelleher J. et al, (2019), Nature genetics, 51, 1330 - 1338
Identification of host-pathogen-disease relationships using a scalable Multiplex Serology platform in UK Biobank
Mentzer A. et al, (2019)
The origins and relatedness structure of mixed infections vary with local prevalence of P. falciparum malaria
MCVEAN G. et al, (2019), eLife
Detection of simple and complex de novo mutations without, with, or with multiple reference sequences
Garimella K. et al, (2019)
Bayesian meta-analysis across genome-wide association studies of diverse phenotypes.
Trochet H. et al, (2019), Genetic epidemiology, 43, 532 - 547