Director, Big Data Institute; Professor of Statistical Genetics, Nuffield Department of Medicine
- Head of Bioinformatics and Statistical Genetics
- University Lecturer in Mathematical Genetics
- Group Head / PI and Unit Director,
My research covers several areas in the analysis of genetic variation, combining the development of methods for analysing high throughput sequencing data, theoretical work and empirical analysis. Of particular interest are: the analysis of recombination from population genetic data, dissecting signals of disease association within the HLA, methods for inferring genealogical history from DNA sequence data and de novo sequence assemblyfor the discovery of genetic variation. I am a member of the Mathematical Genetics Group in the Department of Statistics and Acting Director of the new Oxford Big Data Institute.
Selfish mutations dysregulating RAS-MAPK signaling are pervasive in aged human testes.
Maher GJ. et al, (2018), Genome research
LOW-BIAS RNA SEQUENCING OF THE HIV-2 GENOME FROM BLOOD PLASMA.
James KL. et al, (2018), Journal of virology
The UK Biobank resource with deep phenotyping and genomic data.
Bycroft C. et al, (2018), Nature, 562, 203 - 209
Dating genomic variants and shared ancestry in population-scale sequencing data
Albers P. and McVean G., (2018)
Systematic classification of shared components of genetic risk for common human diseases
Cortes A. et al, (2018)