Director, Big Data Institute; Professor of Statistical Genetics, Nuffield Department of Medicine
- Head of Bioinformatics and Statistical Genetics
- University Lecturer in Mathematical Genetics
- Group Head / PI and Unit Director,
My research covers several areas in the analysis of genetic variation, combining the development of methods for analysing high throughput sequencing data, theoretical work and empirical analysis. Of particular interest are: the analysis of recombination from population genetic data, dissecting signals of disease association within the HLA, methods for inferring genealogical history from DNA sequence data and de novo sequence assemblyfor the discovery of genetic variation. I am a member of the Mathematical Genetics Group in the Department of Statistics and Acting Director of the new Oxford Big Data Institute.
Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
Jason F. et al, (2017), Scientific data, 4, 170179 - 170179
A point mutation in the ion conduction pore of AMPA receptor GRIA3 causes dramatically perturbed sleep patterns as well as intellectual disability.
Davies B. et al, (2017), Hum Mol Genet, 26, 3869 - 3882
Characterisation of the changing genomic landscape of metastatic melanoma using cell free DNA.
Cutts A. et al, (2017), NPJ genomic medicine, 2, 25 - 25
Deconvolution of multiple infections in Plasmodium falciparum from high throughput sequencing data.
Zhu SJ. et al, (2017), Bioinformatics (Oxford, England)
Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank.
Cortes A. et al, (2017), Nature genetics