Director, Big Data Institute; Professor of Statistical Genetics, Nuffield Department of Medicine
- Head of Bioinformatics and Statistical Genetics
- University Lecturer in Mathematical Genetics
- Group Head / PI and Unit Director,
My research covers several areas in the analysis of genetic variation, combining the development of methods for analysing high throughput sequencing data, theoretical work and empirical analysis. Of particular interest are: the analysis of recombination from population genetic data, dissecting signals of disease association within the HLA, methods for inferring genealogical history from DNA sequence data and de novo sequence assemblyfor the discovery of genetic variation. I am a member of the Mathematical Genetics Group in the Department of Statistics and Acting Director of the new Oxford Big Data Institute.
HLA*LA - HLA typing from linearly projected graph alignments.
Dilthey AT. et al, (2019), Bioinformatics (Oxford, England)
Bayesian meta-analysis across genome-wide association studies of diverse phenotypes.
Trochet H. et al, (2019), Genetic epidemiology
Ultrafast search of all deposited bacterial and viral genomic data.
Bradley P. et al, (2019), Nature biotechnology, 37, 152 - 159
Genomic analysis of Plasmodium vivax in southern Ethiopia reveals selective pressures in multiple parasite mechanisms.
Auburn S. et al, (2019), The Journal of infectious diseases
Low-Bias RNA Sequencing of the HIV-2 Genome from Blood Plasma.
James KL. et al, (2019), Journal of virology, 93