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The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic, neurological, ophthalmic, psychiatric, dermatological, oncological, and respiratory diseases. As of 2008, 14,926 subjects aged 45 years or over comprise the Rotterdam Study cohort. The findings of the Rotterdam Study have been presented in over a 1,000 research articles and reports (see www.erasmus-epidemiology.nl/rotterdamstudy ). This article gives the rationale of the study and its design. It also presents a summary of the major findings and an update of the objectives and methods.

Original publication

DOI

10.1007/s10654-013-9866-z

Type

Journal article

Journal

European journal of epidemiology

Publication Date

21/11/2013

Volume

28

Pages

889 - 926

Addresses

Department of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands, a.hofman@erasmusmc.nl.

Keywords

Humans, Chronic Disease, Life Expectancy, Incidence, Prospective Studies, Epidemiologic Research Design, Genetic Research, Pharmacoepidemiology, Population Dynamics, Aged, Aged, 80 and over, Middle Aged, Netherlands, Female, Male