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Seven hundred twenty-three isolates of Moraxella catarrhalis obtained from outpatients with a variety of infections in 30 medical centers in the United States between 1 November 1994 and 30 April 1995 were characterized in a central laboratory. The overall rate of beta-lactamase production was 95.3%. When the National Committee for Clinical Laboratory Standards MIC interpretive breakpoints for Haemophilus influenzae were applied, percentages of strains found to be susceptible to selected oral antimicrobial agents were as follows: azithromycin, clarithromycin, and erythromycin, 100%; tetracycline and chloramphenicol, 100%; amoxicillin-clavulanate, 100%; cefixime, 99.3%; cefpodoxime, 99.0%; cefaclor, 99.4%; loracarbef, 99.0%; cefuroxime, 98.5%; cefprozil, 94.3%; and trimethoprim-sulfamethoxazole, 93.5%.

Original publication

DOI

10.1128/aac.40.12.2884

Type

Journal article

Journal

Antimicrobial agents and chemotherapy

Publication Date

12/1996

Volume

40

Pages

2884 - 2886

Addresses

Clinical Microbiology Laboratories, University of Massachusetts, Worcester 01655, USA.

Keywords

Humans, Moraxella (Branhamella) catarrhalis, Neisseriaceae Infections, Anti-Bacterial Agents, Microbial Sensitivity Tests, Population Surveillance, Drug Resistance, Microbial, United States